Objective, Bayesian Analysis of Fluorescence Correlation Spectroscopy Data

Bayesian Analysis of Survival Data with Spatial Correlation

Often in practice the data on the mortality of a living unit correlation is due to the location of the observations in the study‎. ‎One of the most important issues in the analysis of survival data with spatial dependence‎, ‎is estimation of the parameters and prediction of the unknown values in known sites based on observations vector‎. ‎In this paper to analyze this type of survival‎, ‎Cox...

Bayesian approach to the analysis of fluorescence correlation spectroscopy data II: application to simulated and in vitro data.

Fluorescence correlation spectroscopy (FCS) is a powerful approach to characterizing the binding and transport dynamics of macromolecules. The unbiased interpretation of FCS data relies on the evaluation of multiple competing hypotheses to describe an underlying physical process under study, which is typically unknown a priori. Bayesian inference provides a convenient framework for this evaluat...

Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy.

This article focuses on methods based on fluctuation correlation spectroscopy to determine the formation of protein complexes in living cells. We present the principles of the fluctuation method applied to cells. We discuss the novelty and the promises of this approach. The emphasis is in the discussion of the underlying statistical assumptions of the image correlation spectroscopy analysis rat...

Bayesian model selection applied to the analysis of fluorescence correlation spectroscopy data of fluorescent proteins in vitro and in vivo.

Fluorescence correlation spectroscopy (FCS) is a powerful technique to investigate molecular dynamics with single molecule sensitivity. In particular, in the life sciences it has found widespread application using fluorescent proteins as molecularly specific labels. However, FCS data analysis and interpretation using fluorescent proteins remains challenging due to typically low signal-to-noise ...

Fluorescence correlation spectroscopy.